HUMAN-SPECIFIC EPIGENOMIC STATES IN SPERMATOGENESIS

Human-specific epigenomic states in spermatogenesis

Infertility is becoming increasingly common, affecting one in six people globally.Half of these cases can be attributed to male factors, many driven by abnormalities in the process of sperm development.Emerging evidence from genome-wide association studies, genetic screening of patient cohorts, and animal models highlights an important Wand genetic

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Role of Polyamines in Immune Cell Functions

The immune system is remarkably responsive to a myriad of invading microorganisms and provides continuous surveillance against tissue damage and developing tumor cells.To achieve these diverse functions, multiple soluble and cellular components must react in an orchestrated cascade of events to control the specificity, magnitude and persistence of

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